[UK] The Physical and Chemical Modification of Single Cancer Cells for Protein Analysis - Imperial College London
This PhD studentship will focus on the analysis and measurement of all the different proteins expressed in individual cancer cells. This form of single cell analysis is one of the key challenges in post-genomic science. It will involve working on one of the most exciting technological frontiers in the field; developing the ability to selectively perturb, disrupt, manipulate and digest single cells (Nanodigestion) before analysing their composition. You will use a number of biological, physical and chemical approaches within microfluidic devices.
The research undertaken will have a direct impact on advancing the field of proteomics, which underpins a vast range of modern life-sciences research from personalised medicine to the engineering of more efficient plants.
This project part is of a £5 million multidisciplinary Single Cell proteomics Project funded by the Engineering and Physical Sciences Research Council (EPSRC) to create an unrivalled suite of technologies for the study of single cells using proteomic approaches. You will be working alongside both PhD students and Post-doc researchers from the Imperial College Departments of Chemistry and Physics, the Institute of Cancer Research and the London Research Institute of Cancer Research UK and under the auspices of the Chemical Biology Centre (CBC).
Study information
Qualification:
MRes and PhD
Study duration:
4 years
Study mode:
FT
Start month:
October 2007
Entry requirements:
2.1 or above in a Physical Science Subject
Funding information
Funder:
EPSRC
Funding applies to:
EU applicants (including UK)
Funding duration:
4 years
Application deadline: 30 April 2007
Contacts and how to apply
Academic contact:
Dr Oscar Ces (o.ces@imperial.ac.uk)
Administrative contact and how to apply:
Dr Eugenia Dahm-Vicker
http://www.chemicalbiology.ac.uk/st_scp3.html
